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The buttocks (singular: buttock) are rounded portions of the anatomy located on the posterior of the pelvic region of apes and humans, including many other bipeds or quadrupeds.The buttocks are formed by the masses of the gluteal muscles or 'glutes' (the gluteus maximus muscle and the gluteus medius muscle) superimposed by a layer of fat. The superior aspect of the buttock ends at the iliac crest, and the lower aspect is outlined by the horizontal gluteal crease. The gluteus maximus has two insertion points: 1/3 superior portion of the linea aspera of the femur, and the superior portion of the iliotibial tractus. The masses of the gluteus maximus muscle are separated by an intermediate intergluteal cleft or "crack" in which the anus is situated.

The buttocks allow primates to sit upright without needing to rest their weight on their feet as four-legged animals do. Females of certain species of baboon have red buttocks that blush to attract males. In the case of humans, females tend to have wider and thicker buttocks due to higher subcutaneous fat and wider hips.

Some baboons and all gibbons, though otherwise fur-covered, have characteristic naked callosities on their buttocks. While human children generally have smooth buttocks, mature males and females have varying degrees of hair growth, as on other parts of their body. Females generally have hair growth in the gluteal cleft (particularly around the anus), often extending laterally onto the lower aspect of the cheeks. Males may have hair growth over some or all of the buttocks.